(H/B) THE ORGANIC CHEMISTRY OF DRUG DESIGN AND DRUG ACTION

Παρουσίαση

Standard medicinal chemistry courses and texts are organized by classes of drugs with an emphasis on descriptions of their biological and pharmacological effects. This book represents a new approach based on physical organic chemical principles and reaction mechanisms that rationalize drug action and allow the reader to extrapolate to many related classes of drug molecules. The Second Edition reflects the significant changes in the drug industry over the past decade, and now includes color illustrations, chapter problems, and other elements that make concepts easier to understand. (From the publisher)

Περιεχόμενα

PREFACE
CHAPTER 1 Introduction
CHAPTER 2 Drug Discovery, Design, and Development
CHAPTER 3 Receptors
CHAPTER 4 Enzymes (Catalytic Receptors)
CHAPTER 5 Enzyme Inhibition and Inactivation
CHAPTER 6 DNA-Interactive Agents
CHAPTER 7 Drug Metabolism
CHAPTER 8 Prodrugs and Drug Delivery Systems
INDEX